Ependymoma is a type of tumor that arises from ependymal cells, which line the ventricles of the brain and the central canal of the spinal cord. These cells are part of the central nervous system and play a crucial role in producing cerebrospinal fluid (CSF) that cushions and protects the brain and spinal cord. Ependymomas are relatively rare, accounting for about 2-3% of all primary brain tumors in adults and approximately 10% in children.
Ependymomas can occur at any age but are most commonly diagnosed in children and young adults. They are classified into several types based on their location and microscopic appearance:
The symptoms of ependymoma tumors vary depending on their location and size. Common symptoms include:
In children, symptoms might also include irritability, developmental delays, and changes in school performance.
Diagnosing an ependymoma typically involves several steps:
The treatment of ependymoma tumors usually involves a combination of surgery, radiation therapy, and in some cases, chemotherapy.
The prognosis for individuals with ependymoma varies widely based on several factors, including the location and grade of the tumor, the success of surgical removal, and the patient's age. Generally, complete surgical removal followed by radiation therapy offers the best chance for long-term survival and reduced recurrence.
Ongoing research into the genetic and molecular characteristics of ependymomas is helping to develop more targeted and effective treatments. Clinical trials are exploring new therapies and treatment combinations, aiming to improve outcomes and quality of life for patients.
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